PSORIASIS

Psoriasis (the word derives from the Greek word for 'being itchy') is a chronic and prolonged autoimmune disorder of the skin which affects 2-4% of the population. It affects men and women equally, and for many sufferers, onset occurs in the teenage years or early adulthood and is often (but not always) associated with other conditions, among this arthritis, cardiovascular disease, metabolic syndrome, liver disease, Crohn's disease and depression.

The condition presents as patches of skin which are raised, red, dry, scaly and itchy. These can vary from just small patches of skin, often on the forearms, shins, stomach and the scalp, to widespread coverage on the entire body (where it is referred to as 'erythrodermic psoriasis'). Psoriasis affects fingernails and toenails in many sufferers, forming pits in the nails or discolouring them. It can also affect the joints - finger joints, wrists, elbows, knees and ankles, which become inflamed and painful. Although there are five types of psoriasis, the most common type is known as Psoriasis Vulgaris, which accounts for 80-90% of all cases.

Cause

Psoriasis is believed to be a genetic disorder (i.e. inherited) where outbreaks are set off by triggers in the environment. Around a third of sufferers have relatives who suffer or suffered from the condition, and scientists have recently identified several genes that may be linked to psoriasis.

Triggers of psoriasis outbreaks include infections (e.g. tonsillitis, shingles), some medications (e.g. lithium, beta-blockers) and injury to the skin (referred to as the "Koebner Phenomenon"). It is also believed that sufferers who smoke may have more acute or longer-lasting outbreaks.

Treatment

Unfortunately, there is no 'cure' for psoriasis; however, there are many ways in which the symptoms of psoriasis can be treated, and the lives of sufferers made more comfortable. These treatments include.

  • Moisturising creams (non-prescription)

  • Prescription creams such as coal tar-based preparations, steroid and non-steroid anti-inflammatory, calcipotriol, dithranol

  • UV light therapy (phototherapy)

  • Oral medications such as acitretin, methotrexate, cyclosporin

  • Biologic injections 

 

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